“There is a pretty direct relationship between CREB and long-term memory,” Murphy said, “and many organisms lose CREB as they age.” By studying the CREB-activated genes involved in long-term memory, the researchers hope to better understand why some organisms lose their long-term memories as they age."
For the complete article: https://blogs.princeton.edu/research/2015/01/22/genome-wide-search-reveals-new-genes-involved-in-long-term-memory/?subscribe=success#blog_subscription-2